| Linda Cardellini | Lindsay Weir |
| John Francis Daley | Sam Weir |
| James Franco | Daniel Desario |
| Samm Levine | Neal Schweiber |
| Seth Rogen | Ken Miller |
| Jason Segel | Nick Andopolis |
| Martin Starr | Bill Haverchuck |
| Becky Ann Baker | Jean Weir |
| Joe Flaherty | Harold Weir |
| Busy Philipps | Kim Kelly |